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Super-Resolution Image Reconstruction Based on Single-Molecule Localization Algorithm
2021
Photonics
Fluorescence imaging is an important and efficient tool in cell biology and biomedical research. In order to observe the dynamics of biological macromolecules such as DNA, RNA and proteins in live cells, it is extremely necessary to surpass the Abbe diffraction limit in microscopic imaging. Single-molecule localization microscopy (SMLM) is a sort of super-resolution imaging technique that can obtain a large number of images of sparse fluorescent molecules by the use of photoswitchable
doi:10.3390/photonics8070273
fatcat:i3k5djtzrjekjlu7djkesicygu