Synthesis and Acaricidal Activity of New 1H-Pyrazole-4-carboxamide Derivatives

Feng Xie, Tingting Liu, Guo Yang, Jing Yuan, Xiaolin Kong, Tianming Xu, Chengxia Tan
2013 Youji huaxue  
To find new lead compounds with high acaricidal bioactivity, ten new 1H-pyrazole-4-carboxamide derivatives were designed and synthesized by combining with the 1,3,5-trimethyl-1H-pyrazole-4-carboxamide moiety in pyflubumide and diaryl ether moiety in flufenoxuron. Their structures were confirmed by 1 H NMR, MS and elemental analyses. The acaricidal activities of these compounds were evaluated by pesticide bioassay procedure. The results showed that most of title compounds exhibited significant
more » ... fect against Tetranychus cinnabarinus with 90.0% death rate at 500 mg/L.
doi:10.6023/cjoc201307006 fatcat:rokkptz6xzc2lg25nk2kzxk3uy