HOMSTRAD: adding sequence information to structure-based alignments of homologous protein families

P. I. W. de Bakker, A. Bateman, D. F. Burke, R. N. Miguel, K. Mizuguchi, J. Shi, H. Shirai, T. L. Blundell
2001 Bioinformatics  
We describe an extension to the Homologous Structure Alignment Database (HOMSTRAD; Mizuguchi et al., Protein Sci., 7, 2469-2471 , 1998a to include homologous sequences derived from the protein families database Pfam (Bateman et al., Nucleic Acids Res., 28, 263-266, 2000). HOMSTRAD is integrated with the server FUGUE (Shi et al., submitted, 2001) for recognition and alignment of homologues, benefitting from the combination of abundant sequence information and accurate structurebased alignments.
doi:10.1093/bioinformatics/17.8.748 pmid:11524380 fatcat:d22u4b6pcnbyfnxikrdryddjfa