A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Sister chromatid exchange: A possible approach to characterize familial breast cancer patients
Sister chromatid exchange (SCE) frequency is widely used as an indicator of spontaneous chromosome instability. We investigated SCE frequency in the peripheral blood lymphocytes of familial and sporadic breast cancer (BC) patients from the Apulian Caucasian Population. Eighty-one patients were enrolled: 22 with familial history and 59 sporadic patients. Eleven familial patients had an 'increased risk' of BRCA gene mutation (BRCAPro ≥10%) and were candidates for BRCA1 and BRCA2 mutationdoi:10.3892/or.2014.3628 pmid:25434423 fatcat:lpujzxvrk5h3vmckjulhvd2aj4