Background Psoriasis is a chronic inflammatory disorder of the skin; the hallmark of psoriasis is sustained inflammation that leads to uncontrolled keratinocyte proliferation and dysfunctional differentiation. Psoriasis shows clear autoimmune-related pathomechanisms, in which autoantigen-specific T cells contribute to the development, chronification, and overall course of the disease. Psoriasis is primarily a skin disease, but other internal organs may be involved; affliction of the joints is

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... ll established, but kidney involvement is yet to be universally agreed upon, although some recent studies have linked psoriasis to kidney disease and certain glomerular diseases including secondary renal amyloidosis, Ig A nephropathy, and membranous glomerulopathy. Case presentation and conclusion In this paper, we report a case of primary membranoproliferative glomerulonephritis (MPGN) with nephrotic impure syndrome in a psoriatic patient. The etiological investigation was negative with normal serum complement and ASO titers and were negative for HBV, HCV, HIV, and ANA. The patient improved on prednisolone and angiotensin-converting enzyme inhibitors. To our best of knowledge, cases of MPGN associated with psoriasis are rare and we would like to shed light on this association.