For a simple undirected connected graph G of order n, let D ( G ) , D L ( G ) , D Q ( G ) and T r ( G ) be, respectively, the distance matrix, the distance Laplacian matrix, the distance signless Laplacian matrix and the diagonal matrix of the vertex transmissions of G. The generalized distance matrix D α ( G ) is signified by D α ( G ) = α T r ( G ) + ( 1 - α ) D ( G ) , where α ∈ [ 0 , 1 ] . Here, we propose a new kind of Estrada index based on the Gaussianization of the generalized distance

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... atrix of a graph. Let ∂ 1 , ∂ 2 , ... , ∂ n be the generalized distance eigenvalues of a graph G. We define the generalized distance Gaussian Estrada index P α ( G ) , as P α ( G ) = ∑ i = 1 n e - ∂ i 2 . Since characterization of P α ( G ) is very appealing in quantum information theory, it is interesting to study the quantity P α ( G ) and explore some properties like the bounds, the dependence on the graph topology G and the dependence on the parameter α . In this paper, we establish some bounds for the generalized distance Gaussian Estrada index P α ( G ) of a connected graph G, involving the different graph parameters, including the order n, the Wiener index W ( G ) , the transmission degrees and the parameter α ∈ [ 0 , 1 ] , and characterize the extremal graphs attaining these bounds.