Synthesis of some New Thienopyrimidines containing 4 -Thiazolidinone Moiety

S. EL-BAHAEI, E. E. BAYOUMY, SH. YOUSSIF
1988 Zenodo  
Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt Manuscript received 18 February 1988, accepted 8 July 1988 The reaction of 4-mercaptopyrimidines (1) with halogenated active methylene in aqueous sodium carbonate gave compounds 2. Compound 2c, g were allowed to react with hydrazine hydrate in ethanolts give the acid hydrazides (4a, b). The latter were condensed with aromatic aldehydes and ketones to give the corresponding hydrazones (5). Cyclocondensation of
more » ... colic acid on the hydrazones (5) gave the thiazoli-dinothienopyrimidines (6).
doi:10.5281/zenodo.6076748 fatcat:4x4wfvqdunee3n5aptfkorj7wu