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Findings & Interpretation: Patients were often excluded from studies if diagnostic scans revealed pathological long bone fractures or cord compression. Benefits of exercise included increased lower body strength, perceived quality of life, and adherence to training regimens when supervised by an exercise physiologist or physical therapist. Select studies also revealed a positive influence on body composition and systolic blood pressure. Discussions & Implications: Research supports thatdoi:10.1016/j.bbmt.2014.11.621 fatcat:f4cyy4txrvbr7auxbz7gxth4pm