This article describes the relationship between sleep and neuroendocrine disorders following traumatic brain injury (TBI). There is evidence to support that sleep disorders and neuroendocrine dysfunction can negatively impact recovery and may be the underlying cause of some of the physical, cognitive and emotional symptoms experienced by patients following TBI. We will address the impact of TBI on the neuroendocrine system and sleep-wake cycles within the context of rehabilitation.

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... we will focus on the effects of TBI-induced neuroendocrine and sleep alterations and the influences these disorders have on rehabilitation outcomes. Findings from non-injured and injured patient populations are reviewed and support diagnosing and treating sleep disturbances and neuroendocrine dysfunction while the patient is undergoing rehabilitation. A better understanding of the interplay between neuroendocrine functioning and sleep may improve quality of life and rehabilitative outcomes after TBI.