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Reactivity of Urinary Albumin (Microalbumin) Assays with Fragmented or Modified Albumin
2007
Clinical Chemistry
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BACKGROUND: Controversy exists regarding occurrence and measurement of structural variants of albumin in urine. In this study, we examined cross-reactivity of in vitro modified albumins in assays for urine albumin (microalbumin). METHODS: We analyzed albumin modified by reagents, trypsin, or physical treatments or differing in primary sequence (animal albumins) with an immunoturbidimetric assay (Beckman LX20) using goat antiserum and a competitive immunoassay (Siemens Immulite) using a
doi:10.1373/clinchem.2007.092825
pmid:17981922
fatcat:ge4iepzg25grnggt7qun26oy3y