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Quantitative Magnetic Resonance Imaging Differences Between Alzheimer Disease With and Without Subcortical Lacunes
2002
Alzheimer Disease and Associated Disorders
Previous reports showed that patients with Alzheimer disease (AD) frequently have coexisting vascular-related pathologies, such as cerebral infarcts and white matter lesions. The aim of this study was to determine the effects of subcortical lacunar infarcts on brain structure in patients with AD. Semi-automated tissue segmentation and volumetry of magnetic resonance imaging data were performed in 38 AD patients without lacunes (AD-L), 24 AD patients with subcortical lacunes (AD +L), and 40
doi:10.1097/00002093-200204000-00002
pmid:12040300
pmcid:PMC1820852
fatcat:zieazb6fgzaxjcjdhj2ovsfpoi