A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
The stress response to surgery has two main systemic effects in an organism: neuroendocrine and haemato-immunological. Neuroendocrine effects are induced by changes in the hypothalamic- pituitary-adrenal axis and the sympathetic-adrenal-medullary axis. Haematoimmunological effects are characterised by cytokine production, acute phase reaction and lymphocyte and neutrophil proliferation. All of these responses interact closely. Prolongation of the stress response can increase morbidity anddoi:10.2478/v10046-012-0014-z fatcat:rpjpmg66afbxrc3e4pp7eu65pi