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Characterization of fibroblast growth factor 1 in obese children and adolescents
Fibroblast growth factor 1 (FGF1) can regulate glucose and lipid metabolism in obese mice. Serum FGF1 has increased in type 2 diabetes mellitus adults and correlated with BMI. This study aimed to indicate conventional weight loss effects on FGF1 in obese children and adolescents. Materials and methods Clinical and metabolic parameters of 88 lean and obese individuals (ages 5–15 years) and 39 obese individuals followed with 6 months of lifestyle intervention were collected. Serum FGF1 levelsdoi:10.1530/ec-18-0141 pmid:29991637 fatcat:2cvaltpwanfmtpimw776rp7qqy