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Gene-gene interaction filtering with ensemble of filters
2011
BMC Bioinformatics
Complex diseases are commonly caused by multiple genes and their interactions with each other. Genome-wide association (GWA) studies provide us the opportunity to capture those disease associated genes and gene-gene interactions through panels of SNP markers. However, a proper filtering procedure is critical to reduce the search space prior to the computationally intensive gene-gene interaction identification step. In this study, we show that two commonly used SNP-SNP interaction filtering
doi:10.1186/1471-2105-12-s1-s10
pmid:21342539
pmcid:PMC3044264
fatcat:ndemxuasqne5xijnzan2isdxbi