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The appearance of drug-resistant strains of Mycobacterium tuberculosis (M. tb) poses a great challenge to the development of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologies might alleviate the limitations of current therapies, we have designed a new nanoformulation for use as an anti-TB drug delivery system. It consists of incorporating mycobacterial cell wall mycolic acids (MA) as targeting ligands into a drug-encapsulating Poly DL-lactic-coglycolic aciddoi:10.1016/j.jconrel.2015.06.005 pmid:26055640 fatcat:cy3zdkqr4ndxxcnwhulu74zdsm