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Equation Derivation of the Probability Distribution of IBS Score among Full Sibling Pairs

2019
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Journal of Forensic Medicine
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Objective To derive the general equation of the probability distribution of identity by state (IBS) score among biological full sibling pairs by calculating STR allele frequency. Methods Based on the Mendelian genetics law and the hypothesis that parents of biological full siblings (FS) were unrelated individuals, the IBS score and corresponding probability of different genotype combinations in the offspring when unrelated individuals of different genotype combinations give birth to two

doi:10.12116/j.issn.1004-5619.2019.06.003
pmid:31970950
fatcat:rqhjoddnezccdkchahqk3i62ce