Review A Case of Chorea successfully treated by Arsenic . By George Gregory, M. D. On the efficacy of the bark of the Pomegranate tree in cases of Tania . By P. Breton, Esq

1822 The New England Journal of Medicine and Surgery and the Collateral Branches of Science  
The subject of this case continued to live, with all the symptoms of a malformed heart, until he was eighteen years old, The following is Dr. Gregory's description of the appearances on dissection. ' The iungs were found adhering every where very firmly to the pleura costalis and pericardium. Tubercles and vomicaj were scattered through their substance. The cavity of the pericardium contained four ounces of serum. The heart was very firm, and of a natural size. The aorta and pulmonary artery
more » ... se from the right ventricle. The septum ventriculorura, at its base, was wanting for an extent somewhat larger than the diameter of the aorta. The pulmonary artery was not much smaller than natural, and its origin was surrounded by some cartilaginous like fibres, between which and the semilunar valve a small sac was formed. It was observed that the opening in the septum ventriculorum corresponded so exactly with the situation of the aorta at its origin, that the contractions of the left ventricle must have propelled its'blood almost entirely into that vessel, while the blood of the right ventricle might have been divided equally between the tvvo greal arteries. So free, however, was the communication of the venticles with each other, that in the diastole of the heart, it is presumable that the venous and arterial blood were ultimately mixed.' A Case of Chorea successfully treated by Arsenic.
doi:10.1056/nejm182201010110113 fatcat:6d7xrxrg3vfgdbjx5djykiip7m