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Chronic Lymphocytic Leukemia FISH Panel
2007
American Journal of Clinical Pathology
A b s t r a c t Interphase fluorescence in situ hybridization (FISH) is an alternative to conventional chromosome analysis of chronic lymphocytic leukemia (CLL) cells. We analyzed 172 samples from 136 possible CLL cases using a FISH panel. Reflex testing with probes to CCND1, BCL2, BCL3, BCL11A, c-MYC, MALT1, and a break-apart immunoglobulin heavy chain (IGH) probe was done if more than 2 signals for 14q32 occurred. For 111 cases, there were sufficient data for analysis. Of 111 cases, 81
doi:10.1309/21tn2ruwkr827uw2
pmid:17638669
fatcat:ot5ak7xxv5e5zc6vo4tg364xvi