a tool for navigating sequences from parasitic and free-living nematodes

T. Wylie
2004 Nucleic Acids Research ( is a web accessible resource for investigating gene sequences from nematode genomes. The database is an outgrowth of the parasitic nematode EST project at Washington University ' s Genome Sequencing Center (GSC), St Louis. A sister project at the University of Edinburgh and the Sanger Institute is also underway. More than 295 000 ESTs have been generated from >30 nematodes other than Caenorhabditis elegans including key parasites of humans, animals and plants.
more » ... currently provides NemaGene EST cluster consensus sequence, enhanced online BLAST search tools, functional classifications of cluster sequences and comprehensive information concerning the ongoing generation of nematode genome data. The longterm goal of is to provide the scientific community with the highest quality sequence information and tools for studying these diverse species. Nematodes or roundworms are members of an ancient phylum that accounts for perhaps four out of every five individual animals in the world ( 1 ). Parasitic nematodes infect nearly half the world' s human population, resulting in significant morbidity and mortality. Nematodes also parasitize livestock and companion animals and cause over 80 billion dollars in crop damage annually ( 2 , 3 ). is a specialty database that makes accessible the rapidly expanding nucleotide sequence data and related resources from species across this phylum to target audiences including human/mammalian parasitologists, plant nematologists, Caenorhabditis elegans biologists and other scientists. Abstract Print PDF (164K) Alert me when this article is cited Alert me if a correction is posted
doi:10.1093/nar/gkh010 pmid:14681448 pmcid:PMC308745 fatcat:alqmlkbvfng3zm36kcgfknephu