MMDB: 3D structure data in Entrez

Y. Wang
2000 Nucleic Acids Research  
Three-dimensional structures are now known for roughly half of all protein families. It is thus quite likely, in searching sequence databases, that one will encounter a homolog with known structure and be able to use this information to infer structure-function properties. The goal of Entrez's 3D structure database is to make this information accessible and useful to molecular biologists. To this end, Entrez's search engine provides three powerful features: (i) Links between databases; one may
more » ... earch by term matching in Medline ® , for example, and link to 3D structures reported in these articles. (ii) Sequence and structure neighbors; one may select all sequences similar to one of interest, for example, and link to any known 3D structures. (iii) Sequence and structure visualization; identifying a homolog with known structure, one may view a combined molecular-graphic and alignment display, to infer approximate 3D structure. Entrez's MMDB (Molecular Modeling DataBase) may be accessed at: http:// www.ncbi.nlm.nih.gov/Entrez/structure.html
doi:10.1093/nar/28.1.243 pmid:10592236 pmcid:PMC102448 fatcat:o4lfdvympne35bpwmixhx6wfri