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Hypoxic conditioned medium of placenta-derived mesenchymal stem cells inhibits TGF-β1-induced up-regulation of collagens and differentiation of skin fibroblasts to myofibroblast through IL-10
2016
Int J Clin Exp Pathol
unpublished
Scar formation affects the quality of people's daily lives, and in this study we explored whether hypoxic conditioned medium of placenta-derived mesenchymal stem cells (PMSCs) has a protective effect on scar formation. Our study showed that hypoxic conditioned medium of PMSCs inhibited the transforming growth factor-β1 (TGF-β1)-induced up-regulation of collagens and differentiation of skin fibroblasts to myofibroblast. Mechanism study showed that the level of interleukin-10 (IL-10) was
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