I. Time course of interventions and recovery sleep

Esther Werth, Kimberly A. Cote, Eva Gallmann, Alexander A. Borbély, Peter Achermann
2002 American Journal of Physiology. Regulatory Integrative and Comparative Physiology  
Selective REM sleep deprivation during daytime. I. Time course of interventions and recovery sleep. though repeated selective rapid eye movement (REM) sleep deprivation by awakenings during nighttime has shown that the number of sleep interruptions required to prevent REM sleep increases within and across consecutive nights, the underlying regulatory processes remained unspecified. To assess the role of circadian and homeostatic factors in REM sleep regulation, REM sleep was selectively
more » ... in healthy young adult males during a daytime sleep episode (7-15 h) after a night without sleep. Circadian REM sleep propensity is known to be high in the early morning. The number of interventions required to prevent REM sleep increased from the first to the third 2-h interval by a factor of two and then leveled off. Only a minor REM sleep rebound (11.6%) occurred in the following undisturbed recovery night. It is concluded that the limited rise of interventions during selective daytime REM sleep deprivation may be due to the declining circadian REM sleep propensity, which may partly offset the homeostatic drive and the sleep-dependent disinhibition of REM sleep. non-rapid eye movement sleep; sleep homeostasis; sleep regulation; spectral analysis Address for reprint requests and other correspondence: P. Achermann,
doi:10.1152/ajpregu.00462.2001 pmid:12121866 fatcat:wivedr3bancwzbvpxjwdpidtjy