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Regulation of ribosomal RNA synthesis in Tetrahymena pyriformis
Journal of Cell Science
Ribosomal RNA is synthesized at constant rate during most of the cell cycle in heat-shock synchronized populations of Tetrahymena pyriformis. Early in each macronuclear S-period the rate of synthesis increases abruptly, concomitant with replication of the genes coding for ribosomal RNA. The increase is prevented by inhibitors of DNA replication, added prior to the S-period. Similarly, in cultures synchronized by starvation/refeeding, inhibition of DNA replication, at the time when the rDNA ispmid:97302 fatcat:wkjktfnipfdmzlkvdd2rgahu3u