Investigation of ADMET Profile of Lead Molecule for COVID-19

Nilesh S. Kadu
2020 International Journal for Research in Applied Science and Engineering Technology  
In the present work, an extensive ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) analysis of α-Ketoamides (peptide-type analogues) 13b, which has been recently reported to possess activity for COVID-19, has been performed. The analysis indicates that this could have severe toxic issues. The analysis indicates that this compound 13b needs a lot of modification to become a drug.
doi:10.22214/ijraset.2020.30645 fatcat:eojkss2exbd3zchz2wxqx47xwm