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Human Interleukin 2 (IL-2) Promotion of Immune Regulation and ClinicalOutcomes: A Review
2016
Journal of Cytokine Biology
Interleukin 2 (IL-2) is a monomeric glycoprotein that is primarily produced by activated CD4+ T cells, CD8+ T cells and dendritic cells. It is characterized as a proinflammatory cytokine that is secreted by Th1 cells. IL-2 plays a central role in the activation of regulatory T cells to produce the cytokines tumor necrosis factor alpha (TNF-α) and interferon gamma (IFN-γ). IL-2 may also enhance the cytolytic activity of natural killer cells, thereby ensuring their significance in the control of
doi:10.4172/2576-3881.1000109
fatcat:hhikyoe5kvew5m3z7dlx3rbhbi