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Diabetic Kinome Inhibitors—A New Opportunity for β-Cells Restoration
2021
International Journal of Molecular Sciences
Diabetes, and several diseases related to diabetes, including cancer, cardiovascular diseases and neurological disorders, represent one of the major ongoing threats to human life, becoming a true pandemic of the 21st century. Current treatment strategies for diabetes mainly involve promoting β-cell differentiation, and one of the most widely studied targets for β-cell regeneration is DYRK1A kinase, a member of the DYRK family. DYRK1A has been characterized as a key regulator of cell growth,
doi:10.3390/ijms22169083
pmid:34445786
pmcid:PMC8396662
fatcat:4pwmr7fq35bv5i2se7lzhfkixi