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Expression of the transforming growth factor alpha protooncogene in differentiating human promyelocytic leukemia (HL-60) cells
The process of myeloid differentiation in human promyelocytic leukemia cells (HL-60) is accompanied by the coordinate expression of numerous protooncogenes. To investigate the expression of transforming growth factor alpha (TGF-alpha) in myeloid differentiation, HL-60 cells were induced to differentiate into granulocytes with 1.25% dimethyl sulfoxide, 0.2 microM all-trans retinoic acid, or 500 microM N6,O2-dibutyryladenosine-3'5'-cyclic monophosphate or differentiated along thepmid:7677980 fatcat:6657ehrisfh5pgzyrw5gpjpf7y