SMILE 和 FS-LASIK 术后干眼的对比研究 Comparative study on dry eye after small incision lenticule extraction and femtosecond laser in situ keratomileusis

Smile Fs-Lasik
2017 unpublished
誗AIM: To evaluate the changes of dry eye and tear film stability after small incision lenticule extraction(SMILE) or femtosecond laser in situ keratomileusis(FS-LASIK). 誗METHODS: Sixty cases (120 eyes) accepted refractive surgery from January to June 2015 was retrospectively analyzed, in which 30 cases (60 eyes) were performed SMILE(SMILE group) , 30 cases(60 eyes) were performed FS-LASIK(FS-LASIK group). The symptoms of dry eye, corneal fluorescein staining(FL) , Schirmer 玉test(S玉t) , tear
more » ... est(S玉t) , tear break-up time (BUT) were observed and compared preoperatively, 1wk, 1,3 and 6mo postoperatively. 誗RESULTS: The score of symptoms of dry eye in SMILE group were 0. 36依0. 48, 0. 15 依 0. 36, and 0. 95 依 0. 59, 0. 36 依 0郾 60 in FS-LASIK group at postoperative 1wk and 1mo, the difference was statistically significant, respectively(t =-5. 885, P< 0. 01;t =-2. 370,P = 0. 019). The score of FL in SMILE group were 1. 13依0. 72, 0. 68 依 0. 50, and 1. 85 依 0. 79, 1. 38 依 0. 55 in FS-LASIK group at postoperative 1wk and 1mo, the difference was statistically significant, respectively(t =-5. 149, P< 0. 01; t =-7. 232, P< 0. 01). The S玉t in SMILE group were 13. 11依1. 93, 13. 81依1郾 61, 14. 45依 1. 51, and 8. 76依1. 36, 10. 60依 2郾 08, 11. 85依 2. 42mm / 5min in FS-LASIK group at postoperative 1wk,1mo and 3mo, the difference was statistically significant, respectively (t = 14郾 228, P<0. 01; t = 9. 459, P<0. 01; t = 7. 042, P<0. 01). The BUT in SMILE group were 11. 15 依 1. 71s, 12. 15 依 1. 69s, 12郾 51依1郾 83s, and 8. 55依1. 19s, 9. 68依 1. 40s, 10. 93 依 1. 90s in FS-LASIK group at postoperative 1wk,1mo and 3mo, the difference was statistically significant, respectively (t = 9郾 622,P<0. 01; t = 8. 669,P<0. 01;t = 4. 637,P<0. 01). 誗CONCLUSION: SMILE is more comfortable compared to FS-LASIK with smaller incision, faster corneal recovery and slighter postoperative dry eye sensation. 誗 KEYWORDS: small incision lenticule extraction; femtosecond laser in situ keratomileusis; dry eye Citation:Sun Y, Zhang WJ, Cao H. Comparative study on dry eye after small incision lenticule extraction and femtosecond laser in situ keratomileusis. Guoji Yanke Zazhi(Int Eye Sci) 2017;17(1):50-53 摘要 目的:对比分析 小 切 口 飞 秒 激 光 基 质 透 镜 取 出 术 (small incision lenticule extraction,SMILE) 和 飞 秒 激 光 准 分 子 激 光原位角膜磨镶术(femtosecond laser in situ keratomileusis, FS-LASIK) 术后干眼及泪膜稳定性的变化。 方法:回顾性分析 2015-01 / 06 在我院行角膜屈光手术患 者 60 例 120 眼。 其中 SMILE 组 30 例 60 眼, FS-LASIK 组 30 例 60 眼。 观察两组患者术前、术后 1wk,1、3、6mo 的干 眼症状、角膜荧光素染色(corneal fluorescein staining,FL) 、 基础泪液分泌试验(Schirmer 玉test,S玉t) 、泪膜破裂时间 (tear break-up time,BUT) 的变化,并进行对比分析。 结果:SMILE 组和 FS-LASIK 组术后 1wk、1mo 干眼症状问 卷评分分别为 0. 36依0. 48、0. 95依0. 59 分;0. 15依0. 36、0. 36依 0. 60 分,差异具有统计学意义(t =-5. 885 , P < 0. 01 ; t =-2. 370,P = 0. 019) 。 SMILE 组和 FS-LASIK 组术后 1wk、 1mo 的 FL 评分分别为 1. 13 依0. 72、1. 85 依0. 79 分;0. 68 依 0郾 50、1. 38依0. 55 分,差异具有统计学意义(t =-5. 149,P< 0. 01;t =-7. 232,P <0. 01) 。 SMILE 组和 FS-LASIK 组术 后 1wk, 1、 3mo 的 S 玉 t 分 别 为 13. 11 依 1. 93、 8. 76 依 1郾 36mm / 5min,13. 81依1. 61、10. 60 依2. 08mm / 5min,14. 45 依 1郾 51、11. 85 依 2. 42mm / 5min, 差 异 具 有 统 计 学 意 义 (t = 14郾 228,P<0. 01;t = 9. 459,P < 0. 01;t = 7. 042,P < 0郾 01) 。 SMILE 组和 FS-LASIK 组术后 1wk,1、3mo 的 BUT 分别为 11. 15依1. 71、8. 55依1. 19s;12. 15 依1. 69、9. 68依1. 40s;12. 51依 1. 83、10. 93依1. 90s,差异具有统计学意义 (t = 9. 622,P < 0郾 01;t = 8. 669,P<0. 01;t = 4. 637,P<0. 01) 。
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