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Novel Molecular Targets of Antidepressants
2022
Molecules
Antidepressants target a variety of proteins in the central nervous system (CNS), the most important belonging to the family of G-protein coupled receptors and the family of neurotransmitter transporters. The increasing number of crystallographic structures of these proteins have significantly contributed to the knowledge of their mechanism of action, as well as to the design of new drugs. Several computational approaches such as molecular docking, molecular dynamics, and virtual screening are
doi:10.3390/molecules27020533
pmid:35056845
pmcid:PMC8778443
fatcat:trcnogpclvb53izsiu2nvms2v4