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The brain is comprised of neurons and its support system including astrocytes, glial cells and microglia, thereby forming neurovascular units. Neurons require support from glial cells to establish and maintain functional circuits, but microglia are often overlooked. Microglia function as the immune cell of the central nervous system, acting to monitor the microenvironment for changes in signaling, pathogens and injury. More recently, other functional roles for microglia within the healthy braindoi:10.1007/s11011-014-9539-y pmid:24733573 pmcid:PMC4198517 fatcat:2uy5xo4nv5ejperyumhqoqlpyi