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Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes
2021
Frontiers in Genetics
Copy number aberrations (CNA) are one of the most important classes of genomic mutations related to oncogenetic effects. In the past three decades, a vast amount of CNA data has been generated by molecular-cytogenetic and genome sequencing based methods. While this data has been instrumental in the identification of cancer-related genes and promoted research into the relation between CNA and histo-pathologically defined cancer types, the heterogeneity of source data and derived CNV profiles
doi:10.3389/fgene.2021.654887
pmid:34054918
pmcid:PMC8155688
fatcat:3nebtmrxjvaipml7cvxsfrtate