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Cascade Chromatography and Automated Multidimensional Fractionation
1971
Proceedings of the National Academy of Sciences of the United States of America
A general method of automated multidimensional fractionation has been developed. Its basic ingredients are: (a) cascade fractionation, i.e., the sequential fractionation of components obtained from each chromatographic dimension on the same or a different dimension, (b) on-line acquisition and processing of data at each stage in the fractionation procedure, (c) a method for determining the beginning and end of each peak during column elution, and (d) automatic linkage of the successive stages
doi:10.1073/pnas.68.7.1444
pmid:5283933
pmcid:PMC389214
fatcat:7ksny67lpffqnm5prbmsqctdvi