A retrospective study was performed to investigate the relationship between blood pressure variability (BPV) and imaging features of single small infarction (SSI) on magnetic resonance imaging (MRI). Two hundreds and five patients with SSI and 120 healthy subjects matched with age and sex as the control group were enrolled into this study. All subjects came from the Affiliated Hospital to Qingdao University and Qingdao Municipal Hospital from October 2011 to June 2016. Research subjects were

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... ssified into different groups. Blood pressure was measured once a day and recorded during the hospitalization period (7-10 days). The followed up data of patients after discharging from hospital was collected from the follow-up records. Twenty-four hours BPV (SBPMean , DSBPMax , DSBPSD , NDBPMax , NDBPSD, and DDBPCV ), day-to-day, and visit-to-visit BPV (SBPMax , SBPSD , DBPMax, and DBPSD ) in the SSI group were significantly higher than that in control group. Compared with the giant lacunar group, day-to-day BPV (SBPMean , SBPMax , SBPSD , SBPCV , DBPMean , DBPMax , DBPSD ), and visit-to-visit BPV (SBPMean , SBPMax , SBPSD , DBPMean , DBPMax , DBPSD ) were significantly higher in the small lacunar infarct group (p < .05). The 24 hr BPV (SBPMean , DDBPMax , DDBPMean ), day-to-day BPV (SBPMax , SBPSD , SBPCV ), and visit-to-visit SBPMax in nonround lesion group were significantly higher than that in round group (p < .05). Compared with nondeep lesion group, some parameters in day-to-day BPV and visit-to-visit BPV were significantly higher in the deep small lesion group (p < .05). Increased BPV parameters such as day-to-day and visit-to-visit (SBPMax , SBPSD , DBPMax ) were related to the SSI characterized by small lesion in deep brain region.