Physics of Ion Channels

Serdar Kuyucak, Turgut Bastug
2003 Journal of biological physics (Print)  
We review the basic physics involved in transport of ions across membrane channels in cells. Electrochemical forces that control the diffusion of ions are discussed both from microscopic and macroscopic perspectives. A case is made for use of Brownian dynamics as the minimal phenomenological model that provides a bridge between experiments and more fundamental theoretical approaches. Application of Brownian and molecular dynamics methods to channels with known molecular structures is discussed.
doi:10.1023/a:1027309113522 pmid:23345858 pmcid:PMC3456178 fatcat:py4u4e7wxrdulcmlplzfvkufie