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Visualizing the enteric nervous system using genetically engineered double reporter mice: Comparison with immunofluorescence
2017
PLoS ONE
and aims The enteric nervous system (ENS) plays a crucial role in the control of gastrointestinal motility, secretion and absorption functions. Immunohistochemistry has been widely used to visualize neurons of the ENS for more than two decades. Genetically engineered mice that report specific proteins can also be used to visualize neurons of the ENS. The goal of our study was to develop a mouse that expresses fluorescent neuronal nitric oxide synthase (nNOS) and choline acetyltransferase
doi:10.1371/journal.pone.0171239
pmid:28158225
pmcid:PMC5291392
fatcat:jgqgxhvclfe6pdyyilwpioqvkm