Proenkephalin A 119-159 (penKid) – a novel biomarker for acute kidney injury in sepsis: An observational study [post]

2019 unpublished
Sepsis is a leading cause of death worldwide and a major challenge for physicians to predict and manage. Proenkephalin A 119-159 (penKid) is a reliable surrogate marker for the more unstable endogenous opioid peptide enkephalin, which has previously been shown to predict both acute and chronic kidney disease. The aim of this prospective observational study was to assess penKid as a predictor of acute kidney injury (AKI), multi-organ failure and mortality in sepsis among unselected sepsis
more » ... s presenting to the emergency department (ED). Method We measured penKid in 588 adult patients with sepsis (≥2SIRS criteria + suspected infection
doi:10.21203/rs.2.13581/v1 fatcat:t77ktm4rmjbmlcexp3ymstcnju