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Mechanical ventilation affects respiratory microbiome of COVID-19 patients and its interactions with the host
Understanding the pathology of COVID-19 is a global research priority. Early evidence suggests that the microbiome may be playing a role in disease progression, yet current studies report contradictory results. Here, we examine potential confounders in COVID-19 microbiome studies by analyzing the upper (n=58) and lower (n=35) respiratory tract microbiome in well-phenotyped COVID-19 patients and controls combining microbiome sequencing, viral load determination, and immunoprofiling. We founddoi:10.1101/2020.12.23.20248425 fatcat:22qdtsktdbefhgiw6n3hkxfhci