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Senescent astrocytes in aging brain express senescence-associated secretory phenotype (SASP) and link with increased brain aging and its related diseases. In order to determine whether ginsenosides ameliorate the astrocytic senescence in vitro, human astrocytic CRT cells and primary rat astrocytes were used in the present study. Ginsenosides Rg1, Re, Rb1 and Rg3 (5 µg/mL) could effectively prevent the astrocytic senescence induced by H 2 O 2 exposure. However, these ginsenosides did not reversedoi:10.3390/molecules22091516 pmid:28891967 fatcat:x2speysotre5vndsbrps2xa4nm