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摘要:小鼠连续 7 天腹腔注射吗啡(40 mg/kg)建立条件化位置偏好模型,连续皮下递增注射吗啡(25、50、 75、100、125、150 mg/kg) ,成瘾后腹腔注射纳络酮(6 mg/kg)诱导戒断症状(跳跃行为)建立戒断模型。腹腔 The mice with a continuous 7-day intraperitoneal injection of morphine was induced the conditioned placed reference (CPP) model and the mice with a continuous 7-day subcutaneous injection of morphine(25, 50, 75, 100, 125, 150 mg/kg)was induced withdrawal model (jump behavior) by naloxone administration(6 mg/kg). The results suggested that the administration of the GABA Bdoi:10.3724/sp.j.1141.2008.06621 fatcat:foxgnhbcovhb5ky5wvgggapy3y