Here we discuss a 60year old patient with pulmonary tuberculosis sequelae followed by uncontrolled diabetes mellitus with complicated conditions. Insulin resistance is one of the main factors which plays a significant role in glucose homeostasis and energy metabolism. Non-adherent to medication and insulin resistance are the primary factors are the causes of diabetes complication such as microvascular and macrovascular complications. Glycated haemoglobin plays a significant role in the

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... ation of drug sensitivity and determination of insulin insufficiency. This case describes the multifactorial complications due to uncontrolled diabetes; the need for screening for HbA1c is recommended in the high-risk group.