Dental caries is the most common human infection and is widespread among civilized populations. Caries incidence augmented intensely due to the availability of processed sugar. Dental caries treatment involves biomaterials that could modify the mechanical, physiological, and chemical environments in the oral cavity. Clinical success in the cure of dental caries may lie in the development of biomaterials that can inhibit bacterial biofilm formation in the teeth. Clove is known for ages in the

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... atment of tooth decay. Nanoparticles are reported to exhibit anti-bacterial activity and are hence used in several medical applications. In this perspective, nanoparticles were biosynthesized using the clove and were characterized using FT-IR and SEM analyses. Further, dental filling material exhibiting anti-bacterial activity was fabricated using glass ionomer and synthesized nanopowder. This study reveals that developed nano-dental filling material has the potential to be used in dental applications for the prevention of caries.