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Two opposing effects of monovalent cations on the stability of i-motif structure
ABSTRACTAt acidic pH, cytosine-rich single-stranded DNA can be folded into a tetraplex structure called i-motif (iM). In recent studies, the effect of monovalent cations on the stability of iM structures has been addressed, but a consensus about the issue has not been reached yet. Thus, we investigated the effects of various factors on the stability of iM structures using fluorescence resonance energy transfer (FRET)-based analysis for three types of iM derived from human telomere sequences. Wedoi:10.1101/2022.09.30.510309 fatcat:tgbfmmb23nb2xpwnlkgiqavbay