Rospective designing and types of buccal drug delivery system: The Review

Surajkumar Bhaskarao Rathod, Nilesh Prakashrao Tekade, Nitin Shridharao Bhajipale, Dhirendra Babji Sanghai
2020 GSC Biological and Pharmaceutical Sciences  
Buccal bioadhesive films, releasing topical drugs in the oral cavity at a slow and predetermined rate, provide distinct advantages over traditional dosage forms for treatment of many diseases. The mucosa of the buccal cavity is the most easily accessible transmucosal site. This fast dissolving drug delivery system (FDDS) is suited for the drugs which undergo high first pass metabolism and is used for improving bioavailability with reducing dosing frequency to mouth plasma peak levels, which in
more » ... urn minimize adverse/side effects and also make it cost effective This article aims to review the recent Designs of buccal patches and their developments in the buccal adhesive drug delivery systems, & Buccal drug delivery is a promising area for continued research with the aim of systemic delivery of orally inefficient drugs as well as a feasible and attractive alternative for non-invasive delivery of potent peptide and protein drug molecules.
doi:10.30574/gscbps.2020.12.3.0298 fatcat:kepbkorfzbc3bpnq2zsflwwxwu