Synthesis, Crystal Structure, Spectral and Thermal Characterization, and Antimicrobial Activity of [Cu(HOr)(aepy)(H2O)] ·H2O (aepy = 2-aminoethylpyridine, HOr2– = orotate)
Zeitschrift für Naturforschung. B, A journal of chemical sciences
The copper(II) orotate complex with 2-aminoethylpyridine, [Cu(HOr)(aepy)(H2O)] ·H2O, was synthesized and characterized by means of elemental and thermal analysis, magnetic susceptibility, IR and UV/vis spectroscopic, single crystal X-ray diffraction, and antimicrobial activity studies. The complex crystallizes in the triclinic system, space group P1̅, and the Cu(II) ion is five-coordinate with a distorted square-pyramidal coordination geometry. The aepy ligand and the orotate dianion behave as
... dianion behave as bidentate (N,N′ and N,Oacid) chelating ligands. The crystal structure is stabilized by intermolecular O-H···O and N-H···O hydrogen bonds, and the orotate ligand exhibits a double hydrogenbonding functionality. The new compound was found active against some gram (+)/(−) bacteria and yeast Candida albicans ATCC 10231, but there was no activity on Aspergillus niger.