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Full Length Research Paper SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME OXO-AND THIOXOPYRIMIDINES
Int.J.Drug Dev. & Res
unpublished
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Some oxo and thioxotetrahydropyrimidines 4(a-j) were prepared using multicomponent reaction of -keeto ester, arylaldehyde and urea/thiourea in the presence of the NaY zeolite. The microbiological activity of these compounds was tested in vitroagainst Escherichia Coli (PTCC 1338), Pseudomonas aeruginosa (PTCC 1074), Entrococcus faecalis (PTCC 1237) and Staphylococcus aureus (PTCC 1119) bacteria.
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