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Synthesis of 3-Hexyl-4-cyan-6,7-dimethoxy Isocoumarin
2014
Asian Journal of Chemistry
Preserved Fulltext
trihydroxy-3-methyl-isocoumarin, which was isolated from Flaveria bidentis (L) Kuntze, had herbicidal activity and its structure was modified in this research in order to get the isocoumarin compouds with higher herbicidal activity. The reaction starts with 2-amino-4,5-dimethoxy benzoate and then diazo iodination, esterfication, heck coupling, cyclization reaction and cyna substitution reaction were tested to obtain 3-hexyl-4-cyan-6,7-dimethoxy isocoumarin. The isocoumarin derivative is an
doi:10.14233/ajchem.2014.16703
fatcat:dbeoa7efe5fyvahm4rzn525gcu