The aim of the study. To study the literature in order to identify modern scientific views on the clinic, systematics, diagnosis and pathopersonalogy of endogenous psychoses with episodic course. Results. The analysis of the literature shows that the diagnostic and classification approaches of endogenous psychoses with episodic course, are focused on polymorphic and variable symptoms of exacerbation of the disease. This leads to diagnostic mistakes, errors in the appointment of maintenance

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... py, deterioration of compliance and further deepening of social maladaptation of patients. Refusal to develop the mechanisms of pathogenesis on the basis of the nosological approach will inevitably lead to a regression of the level of treatment and rehabilitation approaches - from ethiopathogenetic to symptomatic. Conclusions. Thus, at present, the importance of diagnostic techniques aimed at assessing and differentiating persistent symptoms of the disease in the period of remission of endogenous psychoses and relate to pathopersonalogical transformations. Research and correct diagnostic assessment of this multicomponent cluster of psychopathological symptoms allows to assess the nosological affiliation of a particular clinical case and to determine the necessary pharmacological and social rehabilitation effects in order to correct existing pathopersonalogical transformations and prevent exacerbation of endogenous psychosis.