4 The Risk of Severe Treatment Related Adverse Events is Significantly Lower in Children Compared to Adults When Treated With Standardized Timothy Grass Allergy Immunotherapy Tablets

Jens Strodl Andersen, Peter Astrup Fejerskov, Hendrik Nolte
2012 The World Allergy Organization Journal  
IFN). The nasal symptoms were evaluated monthly for 3 months, with test score symptoms questionary 4 (TSSQ4) and auto-evaluation by scale Linker. Results: We studied 94 AR patients (50% women and 50% men, range age between 5 and 40 years). Indoor antigens (mites, house dust and cockroach) were the main cause of allergy. Allergic patients had more eosinophiles and IgE than the healthy controls (P , 0.05). The number of CD81 lymphocytes was slightly reduced in group 2 after treatment (P , 0.05),
more » ... hereas the amount of IL-4 and IFN ƒnwere increased in both groups (P , 0.005) and the amount of IL-10 was significantly increased in group 1 (P , 0.01) after treatment. Clinical evaluation was with initial TSSQ4 of 11.6 before handling and 5.1 (44%) after, with significant improvement (P , 0.0001) and Likert score was reduced 69% than the star the treatment. Conclusions: The TF along with SLITAE in the treatment of patients with RA did not alter the clinical improvement induced by SLITAE alone for 3 months of treatment, but the combination increased production of IL 10 and production of IFNg.
doi:10.1097/01.wox.0000411749.82659.23 fatcat:mq2qc4mtoncold6mw56eddggsi