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Folding & design
Uncharacterized proteins from newly sequenced genomes provide perfect targets for fold and function prediction. Results: For 38% of the entire genome of Mycoplasma genitalium, sequence similarity to a protein with a known structure can be recognized using a new sequence alignment algorithm. When comparing genomes of M. genitalium and Escherichia coli, > 80% of M. genitalium proteins have a significant sequence similarity to a protein in E. coli and there are > 40 examples that have not beendoi:10.1016/s1359-0278(98)00034-0 pmid:9710568 fatcat:wyz56a5sv5fqteuasyketi6emi