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Structural MRI substrate of long-duration response to levodopa in Parkinson's disease: an exploratory study
2021
Journal of Neurology
The long-duration response (LDR) to L-dopa is a sustained benefit deriving from chronic administration of therapy to patients with Parkinson's disease (PD). Almost all patients with early PD may develop the LDR to L-dopa, even if some patients could not at given dosages of the drug. Aim of this exploratory study is to investigate whether a neuroanatomical substrate may underlie the development of the of LDR using structural magnetic resonance imaging (MRI) and voxel-based morphometry (VBM)
doi:10.1007/s00415-021-10550-5
pmid:33864515
pmcid:PMC8505285
fatcat:rgitzqeobbcennoeogpztifc5u